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June 12, 2006
Hear This! New Hearing Loss Drug Enters Clinical Testing from Sound Pharmaceuticals
After receiving additional funding from DARPA this past winter Sound Pharmaceuticals has initiated clinical testing of SPI-1005 for the prevention and treatment of noise induced hearing loss.
According to OSHA and the CDC, 30-40 million Americans are exposed to hazardous sound levels on a daily basis. Combined with a burgeoning population of war veterans and the dangerous listening habits of the MP3 generation, the societal costs for hearing devices and compensation awards have soared into the billions. There are currently no drugs for the prevention and treatment of hearing loss despite the vast and increasing need. Sound Pharmaceuticals is vigorously addressing this need with its first in class, first in indication drug, SPI-1005.
In multiple preclinical studies, low oral doses of SPI-1005 have been shown to be effective in preventing and treating noise induced hearing loss. Sound Pharmaceuticals has now started a 32 patient Phase 1 study of SPI-1005 in normal healthy volunteers. “This dose escalation safety study will lay the ground work for our Phase 2 safety and efficacy trials with the US Army and Navy later this year,” stated VP and Director of Clinical Operations, Brett MacPherson.
Sound Pharmaceuticals, Inc., is a privately held neuropharmaceutical company with a focus on developing the first drugs for hearing loss and brain injury. For more information please contact Jonathan Kil, MD, President and CEO 206-634-2559.
Full disclosure: Eric Lynch, VP and Director of Research at Sound is also my brother.
Update 6/22: Excellent Technology Review article on Sound.
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